Project Details
PRECISION
MRI‑targeted or standard biopsy for prostate cancer diagnosis
Status:
Completed
International, multicentre randomised trial published in the New England Journal of Medicine, 2018. Results informed guideline changes globally recommending MRI prior to biopsy in biopsy‑naïve men.
International Collaboration
25
centres
11
countries
Published in NEJM,
2018
3492
Citations
Altmetric
776
Summary
Problem
Gap
Methodology
Key results
Impact
Top Recruting Centres
Sapienza University, Italy
61
patients recruited
Principal Investigator
Professor Valeria Panebianco
Mayo Clinic, Rochester, USA
54
patients recruited
Principal Investigator
Dr Lance Mynderse
Oulu University Hospital, Finland
53
patients recruited
Principal Investigator
Dr Markku Vaarala
San Raffaele Hospital, Italy
51
patients recruited
Principal Investigator
Professor Alberto Briganti
Awards
EAU Fritz Schröder Prostate Cancer Research Award (2019)
BMJ UK Research Paper of the Year (2019)
For patients and public
MRI-targeted biopsy results in:
Fewer men needing biopsy
Fewer biopsy cores required
More men with clinically significant cancer detected
Fewer men with clinically insignificant cancer detected
Wish to be involved in contributing to research ideas, please get in touch
compass@ucl.ac.uk
At COMPASS, decade-long research outputs have proven a track record of pioneering surgical standards in prostate and urology care.
©2025, COMPASS Research Group
